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BRIELLA  WISE

309 Walnut Street                                                                                                     (630) 279-9876

Elmhurst, Illinois 60001                                                                                       briella@gmail.com

PROFESSIONAL EXPERIENCE

ABBOTT LABORATORIES, ADD, Abbott Park, IL                                  12/2010 to present   

Technical Support Scientist (Contractor) (2010-2011)

·        Evaluated suppliers’ processes and analytical methods for Abbott critical codes.

·        Examined Abbott Laboratories’ incoming testing.

·        Determined if a gap existed for the critical quality attributes (CQA) of the suppliers’ products.

·        Checked Corrective and Preventive Action (CAPA) reports to determine if a new CQA was identified.

·        CR author.

·        Used Cognos 8, GQMS, ePAS, DRS.

FERRO PFANSTIEHL, Waukegan, IL                                                         10/2010 to 12/2010  

Process Chemist (Contractor) (2010)

·        Characterized and optimized process on small scale of potent compound (Category 3).

·        Developed HPLC method to monitor process of potent intermediates.

REGIS TECHNOLOGIES, Inc., Morton Grove, IL                                       1/2004 to 6/2010

Process Research Chemist (2004 - 2010)

·        Conducted research in validation and route identification for APIs.

·        Ran lab pre-qualification of the customers’ process through the use of statistical analysis and design-of-experiments (DOE) to determine critical process parameters (cpp).

·        Contributed to the design of the process validation protocol for the plant.

·        Conducted route identification for the manufacture of generic APIs.

PFIZER/PHARMACIA/MONSANTO, Skokie, IL                                        7/1993 to 8/2003

Principal Research Scientist (2003)

·        Researched key pharmaceutical intermediates with an emphasis on route identification for a manufacturing process. 

·        Planned and performed hydrogenations for the late development process group within the time frame required by consulting with the group and running multiple experiments at once.

Senior Research Scientist (1995 – 2003)

·        Identified and optimized viable processes for pilot plant and manufacturing plant in order to produce API under current good manufacturing practices (cGMP). Audited pilot plant batch records.

·        Characterized and demonstrated both enabling and manufacturing processes through the use of DOE from micro-scale to multi-kilo scale in the laboratory.

·        Transferred technology to pilot plant, manufacturing plant and contractors under cGMP guidelines in order to meet timelines for Phase I through Phase III supplies.

·        Identified deficiencies in pilot plant batch records through thorough reviews and audits.

·        Coordinated and kept current on all steps of a multi-step synthesis (Chemist Champion) by active review with project chemists, engineers, pilot plant operators and safety department.

·        Developed solutions to long-term problems for marketed products in manufacturing.

Research Chemist (1993 – 1995)

·        Provided support in the development of pharmaceutical intermediate processes while in preclinical development.

·        Responsible for process development of pilot plant routes for pharmaceutical intermediates by the use of qualitative and quantitative methods using HPLC, GC, LCMS, GCMS, NMR, TLC and KF.

·        Solved problems when encountered and implemented solutions for enabling route in pilot plant while keeping project on time.

ACME RESIN CORPORATION, Forest Park, IL                                          7/1987 to 6/1993  

Development Chemist (1987 – 1993)

·        Developed new processes and products of phenol-formaldehyde and urea-formaldehyde based resins, which met all customer specifications with an emphasis on resin performance and cost.

·        Performed technical service and new product trials at the customer's facility to improve their efficiency and reduce their waste.

PPG INDUSTRIES, Inc., Specialty Chemicals Division, Chicago, IL        10/1983 to 6/1987

Senior Chemist (1986 – 1987)

·        Researched the synthesis and transferred the technology to the plant for phosgene derivatives while ensuring a safe environment.

Chemist (1983 – 1986)

·        Supported the development of improved processes for organic flame retardants.

EDUCATION

Master of Business Administration, Illinois Institute of Technology, Chicago, IL, 1989.

Bachelor of Arts, Chemistry, University of Vermont, Burlington, VT, 1983.

CERTIFICATION

ASQ CQA

PROFESSIONAL AFFILIATION

American Chemical Society     

American Society Quality

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